Intraepithelial carcinoma (Bowen disease) - Intraepithelial Carcinoma (Fa'Ama'I Bowen)
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Tulaga masani – Intraepithelial Carcinoma (Fa'Ama'I Bowen) (Intraepithelial carcinoma (Bowen disease)) e masani ona fa'ailoa sese o se eczema tumau, e le mageso.
relevance score : -100.0%
ReferencesBowen's disease (BD) o se ituaiga o kanesa o le pa'u e amata i le vaega pito i fafo o le pa'u (epidermis). E sili atu ona taatele i tagata Caucasians ma e masani ona tupu i vaega o le pa'u e fa'aaalia i le susulu o le la, ae e mafai foi ona aliali i isi mea. O le BD e masani ona fa'aaalia o se fa'ama'i tasi. E masani ona va'aia le BD o se fa'ailoga lapata'i a'o le'i tupu se ma'i tuga o le kanesa o le pa'u. Ina ia su'esu'eina le BD, e masani ona fa'alagolago i le su'esu'eina o fa'ata'ita'iga a le tino i lalo o le microscope (biopsy).
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease tele e afaina ai tagata matua ua silia ma le 60 tausaga. O a'afiaga taua e aofia ai le fa'apa'i umi o le la, fa'avaivaia le puipuiga, fa'ama'i arsenic, ma le pa'u o le HPV. O fa'ama'i HPV 16, 18, 34, ma le 48 e feso'ota'i ma le fa'ama'i o Bowen i itutino. O le fa'ama'i o le HPV i tagata e le o ni tama'ita'i e le'o manino.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
E masani ona aliali mai i se vaega erythematous, pa'u po'o le pala i so'o se vaega o le tino. O le nofoaga sili ona fa'atele o le vae pito i lalo.
E mafai ona togafitia i le faʻaaogaina o togafitiga eseese e pei o le cryotherapy, curettage, cautery, photodynamic therapy, po'o le aveeseina o le liona.
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#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy