Intraepithelial carcinoma (Bowen disease) - Intraepithelial Carcinoma (Fa'Ama'I Bowen)
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Tulaga masani ― Intraepithelial Carcinoma (Fa'Ama'I Bowen) (Intraepithelial carcinoma (Bowen disease)) e ono fa'ailoa sese ose eczema e tumau, e le mageso.
References
Bowen's disease (BD) ose ituaiga o kanesa o le pa'u e amata ile vaega pito i fafo ole pa'u (epidermis) . E sili atu ona taatele i tagata Caucasians ma e masani ona tupu i vaega e faʻaalia i le susulu o le la, ae e mafai foi ona aliali mai i se isi mea. O le BD e masani lava ona faʻaalia o se faʻamaʻi tasi. E masani ona va'aia le BD o se fa'ailoga lapata'i a'o le'i tupu a'e se ma'i tuga o le kanesa o le pa'u. Ina ia su'esu'eina le BD, e masani ona fa'alagolago foma'i i le su'esu'eina o fa'ata'ita'iga a le tino i lalo ole microscope (biopsy) .
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease (BD) is an in-situ squamous cell carcinoma of epidermis. The etiology of BD is multifactorial with high incidence among Caucasians. BD is common in photo-exposed areas of skin, but other sites can also be involved. Lesions are usually solitary. The morphology of BD differs based on age of the lesion, site of origin, and the degree of keratinization. BD is considered as the lull before the storm, which precedes an overt squamous cell carcinoma. Histopathology is the gold standard diagnostic modality to confirm the diagnosis.
Bowen's disease tele e a'afia ai tagata papa'e ua silia ma le 60 tausaga. O a'afiaga taua e aofia ai le fa'apa'i umi o le la, fa'avaivaia le puipuiga, fa'ama'i arsenic, ma le pa'u o le HPV. O fa'ama'i HPV 16, 18, 34, ma le 48 e feso'ota'i ma le fa'ama'i o Bowen i itutino. O le a'afia o le HPV i ma'i e le o ni tama'ita'i e le'o manino.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
Bowen disease is most commonly found in white patients over 60 years old. Other risk factors include chronic sun exposure, immunosuppression, arsenic exposure and cutaneous human papillomavirus (HPV) infection. HPV types 16, 18, 34 and 48 cause Bowen disease at genital sites; the role of HPV in nongenital cases of Bowen disease is less well defined. HPV types 2, 16, 34 and 35 have been rarely identified within nongenital lesions.
E masani ona aliali mai o se vaega erythematous, pa'u po'o le pala i so'o se vaega o le tino. O le nofoaga sili ona taatele o vae pito i lalo.
E mafai ona togafitia e ala i togafitiga eseese e pei o le cryotherapy, curettage, cautery, photodynamic therapy, poʻo le aveeseina o le liona.
○ Suiga ma Togafiti
#Dermoscopy
#Skin biopsy
#Mohs surgery
#Photodynamic therapy